In this episode of MEDcast, expert geriatric psychiatrist and neurologist delve into the recent advances in the treatment of Alzheimer’s dementia. We will discuss treatments that are on the cusp of FDA approval and others that are coming down the pipeline.

Experts reviews the current treatment landscape for management of PBC, highlighting ursodeoxycholic acid (UDCA) and obeticholic acid (OCA), as well as liver transplant.

Drs Kris Kowdley, Steven Flamm, Sonal Kumar, Edward Mena, and David Victor discuss their approach to initiating treatment of PBC as well as managing this chronic condition.

There were higher percentages of patients treated with mirikizumab that had clinical remission at week 12 of the induction trial compared to the placebo group. This was also true at week 40 of the maintenance trial.

New late-breaking phase 3 data showed success with nemolizumab, an investigational drug designed for targeting IL-31 signaling and aimed at the underlying causes of the condition.

An analysis of data from nearly 750,000 adolescents from more than 40 countries offers insight into the changing, and possibly inaccurate, perceptions of healthy body weight among younger people since the turn of the century.

The citrate-free high-concentration formulation and citrate-containing low-concentration of biosimilar adalimumab-bwwd are now available to patients living in the US.

From a novel acne cream to a breakthrough depression drug, a half-dozen agent decisions are coming through in the coming 6 months.

Unacceptable pain is a significant problem for some patients with rheumatoid arthritis, but what proportion of patients are affected? Test your knowledge with this quiz.

In this MEDcast episode, Dr Chovatiya and Dr Bunick delve into the advancements in targeted treatments for vitiligo, exploring their potential to provide long-term efficacy and durable clinical response.

Anita Afzali, MD, discusses treatment approaches to ulcerative colitis (UC) and how they may differ from Crohn’s Disease (CD).

In this MEDcast episode, Dr Chovatiya and Dr Bunick delve into the advancements in targeted treatments for vitiligo, exploring their potential to provide long-term efficacy and durable clinical response.

Experts summarize their clinical strategies for monitoring and treating patients with Crohn’s Disease (CD).

Dr. Juliana Biondo discusses what the future of treatment for hemophilia A looks like based on ongoing trials.

New clinical trial data shows benefits of spesolimab for GPP flares, providing compelling evidence for IL-36 signaling’s effect on the condition’s pathogenesis.

This endocrine case report from Brady Pregerson, MD, features a man in his 60s with diabetes mellitus presenting with 5 days of nonradiating intermittent lower abdominal pain. Can you determine the correct diagnosis?

Headache, pruritis, fatigue, eosinophilia, injection-site reactions, upper abdominal pain, arthralgia, and asthenia were more common in the bulevirtide group compared to the control group.

Drs James Januzzi, Javed Butler, Robert J. Mentz, and Muthiah Vaduganathan share approaches to sequencing quadruple therapy in heart failure to the individual patient, as well as optimizing therapy early in the hospitalization stage.

Javed Butler, MD, MPH, MBA, discussesSGLT-2 inhibitors and their use in heart failure.

Experts discuss the use of biologic agents to manage asthma and describe the mechanisms of action of different biologics.

Medical expert highlights the risk of overuse of oral corticosteroids in the management of asthma and reviews alternative treatment options.

This cardiology case report from Brady Pregerson, MD, features a man in his late 80s presenting to urgent care with multiple episodes of near syncope in the past 3 days. Check out the ECG and determine the correct diagnosis!

New data indicates that hospital culture must be considered when facilities make significant changes, especially when they concern institutional values.

However, the presence of diabetic retinopathy was observed to have no significant impact on physical health and quality of life compared to subjects without retinopathy.

The American Indian and Alaska Native population show the largest increase in median state ratios, rising from 14 - 49.2, while the Black population consistently had the highest median state ratios, increasing from 26.7 - 55.4.